In mice, deletion of the gene encoding apoE leads to a massive hypercholesterolemia and formation of severe vascular lipid lesions resembling human atherosclerosis. In humans, too, the allelic variants of apoE are& ...
aope mouse gene
Genetic Deletion of Chemokine Receptor Ccr6 Decreases Atherogenesis in ApoE-Deficient Mice. Wuzhou Wan,; Jean K. Lim,; Michail S. Lionakis,; Aymeric Rivollier,; David H. McDermott,; Brian L. Kelsall,; Joshua M. Farber,& ...
For the Burmans some of this is likely the case as well, but some of the admixture is almost certainly recent (e.g. the original file shows that some Burmans have “Baloch,” which is a tell for more recent South Asian gene flow).
In mice, deletion of the gene encoding apoE leads to a massive hypercholesterolemia and formation of severe vascular lipid lesions resembling human atherosclerosis. In humans, too, the allelic variants of apoE are& ...
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